Pediatrics & Neonatology
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New knowledge for pediatricians and neonatologists.
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πŸ‘‰Health and nutrition claims for infant formula are poorly substantiated and potentially harmful

πŸ“ŒDespite improvements in infant formula over its 150 year history, it is still associated with health risks for mother and infant compared with breastfeeding.

πŸ”—https://www.bmj.com/content/369/bmj.m875

πŸ‘‰open access

#formula #breastfeeding #nutrition #newborn #neonatology
πŸ‘‰The challenge of medical and dietary management of eczema in infancy

πŸ“ŒIs this eczema? Should I worry about it? What creams should I use and are there certain foods that that I should avoid giving my baby?

These are a couple of common questions doctors and dietitians get from parents with a baby that has eczema.

πŸ”—http://www.rosan-paediatricdietitian.com/the-challenge-of-medical-and-dietary-management-of-eczema-in-infancy/

#webinar #allergy #eczema #nutrition
πŸ‘‰In-Hospital Formula Feeding and Breastfeeding Duration

πŸ“Œ IHFF was associated with earlier weaning, with infants exposed to IHFF at 2.5 to 6 times higher risk in the first year than infants exclusively breastfed. Strategies to reduce IHFF include prenatal education, peer counseling, hospital staff and physician education, and skin-to-skin contact.

πŸ”—https://pediatrics.aappublications.org/content/early/2020/06/05/peds.2019-2946

#feeding #formula #supplement #newborn #nutrition #breastfeeding #aap #pediatrics
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πŸ‘‰NICE guidelines on neonatal #parenteral #nutrition: a step towards standardised care but evidence is scarce

πŸ“ŒGlobally, neonatal conditions are the leading cause of reductions in disability-adjusted life-years and affect outcomes that extend throughout life.
Providing neonatal care to optimise such long-term outcomes is challenging because short-term research outcomes might conflict, even within individual trials.
Evidence-based #guidelines are a welcome tool to translate research into practice and reduce variation in care. Such standardisation of care can improve outcomes for patients. For example, adherence to a standardised guideline for enteral feeding is protective against necrotising enterocolitis, despite the heterogeneity in the content of the individual guidelines.
The latest guideline by the UK's National Institute for Health and Care Excellence (NICE) on neonatal parenteral nutrition is a welcome addition to neonatal practice, and is particularly important given the deficiencies frequently found in the provision of neonatal nutritional care in the UK.

'We must acknowledge that we do not, at present, know the optimal way to provide parental nutrition to neonates and use this clarion call to advocate for high quality research’

πŸ”—https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(20)30179-6/fulltext
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πŸ‘‰A randomized trial of #parenteral #nutrition using a mixed #lipid #emulsion containing fish oil in infants of extremely low birth weight: Neurodevelopmental outcome at 12 and 24 months corrected age, a secondary outcome analysis

πŸ“ŒParenteral nutrition using a mixed lipid emulsion containing fish oil did not improve neurodevelopment of ELBW infants at 12 and 24 months corrected age.

'Another randomized trial failing to show SMOF is superior to Intralipid for short/long term outcomes in preterm infants.'

πŸ”—https://www.jpeds.com/article/S0022-3476(20)30759-9/fulltext
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πŸ‘‰Oxygen saturation to fraction of inspired oxygen ratio in preterm infants on routine #parenteral #nutrition with conventional or fish oil containing #lipid #emulsions

πŸ“ŒContrary to our hypothesis, the use of FO containing IV lipid emulsions for the routine PN of the preterm infant did not improve lung growth compared to the infants who received conventional IV lipid emulsions.

πŸ”—https://doi.org/10.1002/ppul.24938
πŸ…°οΈ

πŸ‘‰A Randomized Trial of #Parenteral #Nutrition Using a Mixed Lipid Emulsion Containing #Fish Oil in Infants of Extremely Low Birth Weight: Neurodevelopmental Outcome at 12 and 24 Months Corrected Age, A Secondary Outcome Analysis

πŸ“ŒParenteral nutrition using a mixed lipid #emulsion containing fish oil did not improve neurodevelopment of extremely low birth weight infants at 12 and 24 months corrected age.

πŸ”—https://doi.org/10.1016/j.jpeds.2020.06.056
πŸ‘‰Very low birth weight infants receive full #enteral #nutrition within 2 postnatal weeks

πŸ“ŒAn evidence-based advancement #feeding protocol was associated with achieving full feeds within the first 2 postnatal weeks for very low birth weight infants.

πŸ”—https://doi.org/10.1038/s41372-020-00819-4
There are several areas of uncertainty in practice, including the optimal and relative intakes of macronutrients and the optimal timing of initiation of parenteral #nutrition after birth. High quality randomised controlled trials powered to detect differences in long term functional outcomes are needed to determine best practice in preterm parenteral nutrition practice.

https://doi.org/10.1016/j.earlhumdev.2021.105468
β–Ίβ–Ί In this large, whole-Β­population, propensity-Β­matched observational study we found no differences in survival to discharge without major morbidity comparing early versus late initiation of PN.
β–Ίβ–Ί We found higher rate of survival in early PN group and also higher rates of major morbidities that are known to be associated with neurodevelopmental impairment.
β–Ίβ–Ί We cannot exclude residual confounding related to survival bias or how sick or unstable a baby was at the time of clinical decision-Β­making about PN initiation.

#nutrition
doi:10.1136/archdischild-Β­2021-Β­322383
Early initiated, moderately early or late advanced with moderate volume increment feeding regimens might be most appropriate in decreasing the risk of NEC stage II or mortality. In view of the certainty of evidence being very low, adequately powered RCTs evaluating these two strategies are warranted.

#nutrition