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👉NICE guidelines on neonatal #parenteral #nutrition: a step towards standardised care but evidence is scarce
📌Globally, neonatal conditions are the leading cause of reductions in disability-adjusted life-years and affect outcomes that extend throughout life.
Providing neonatal care to optimise such long-term outcomes is challenging because short-term research outcomes might conflict, even within individual trials.
Evidence-based #guidelines are a welcome tool to translate research into practice and reduce variation in care. Such standardisation of care can improve outcomes for patients. For example, adherence to a standardised guideline for enteral feeding is protective against necrotising enterocolitis, despite the heterogeneity in the content of the individual guidelines.
The latest guideline by the UK's National Institute for Health and Care Excellence (NICE) on neonatal parenteral nutrition is a welcome addition to neonatal practice, and is particularly important given the deficiencies frequently found in the provision of neonatal nutritional care in the UK.
'We must acknowledge that we do not, at present, know the optimal way to provide parental nutrition to neonates and use this clarion call to advocate for high quality research’
🔗https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(20)30179-6/fulltext
👉NICE guidelines on neonatal #parenteral #nutrition: a step towards standardised care but evidence is scarce
📌Globally, neonatal conditions are the leading cause of reductions in disability-adjusted life-years and affect outcomes that extend throughout life.
Providing neonatal care to optimise such long-term outcomes is challenging because short-term research outcomes might conflict, even within individual trials.
Evidence-based #guidelines are a welcome tool to translate research into practice and reduce variation in care. Such standardisation of care can improve outcomes for patients. For example, adherence to a standardised guideline for enteral feeding is protective against necrotising enterocolitis, despite the heterogeneity in the content of the individual guidelines.
The latest guideline by the UK's National Institute for Health and Care Excellence (NICE) on neonatal parenteral nutrition is a welcome addition to neonatal practice, and is particularly important given the deficiencies frequently found in the provision of neonatal nutritional care in the UK.
'We must acknowledge that we do not, at present, know the optimal way to provide parental nutrition to neonates and use this clarion call to advocate for high quality research’
🔗https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(20)30179-6/fulltext
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👉A randomized trial of #parenteral #nutrition using a mixed #lipid #emulsion containing fish oil in infants of extremely low birth weight: Neurodevelopmental outcome at 12 and 24 months corrected age, a secondary outcome analysis
📌Parenteral nutrition using a mixed lipid emulsion containing fish oil did not improve neurodevelopment of ELBW infants at 12 and 24 months corrected age.
'Another randomized trial failing to show SMOF is superior to Intralipid for short/long term outcomes in preterm infants.'
🔗https://www.jpeds.com/article/S0022-3476(20)30759-9/fulltext
👉A randomized trial of #parenteral #nutrition using a mixed #lipid #emulsion containing fish oil in infants of extremely low birth weight: Neurodevelopmental outcome at 12 and 24 months corrected age, a secondary outcome analysis
📌Parenteral nutrition using a mixed lipid emulsion containing fish oil did not improve neurodevelopment of ELBW infants at 12 and 24 months corrected age.
'Another randomized trial failing to show SMOF is superior to Intralipid for short/long term outcomes in preterm infants.'
🔗https://www.jpeds.com/article/S0022-3476(20)30759-9/fulltext
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👉Oxygen saturation to fraction of inspired oxygen ratio in preterm infants on routine #parenteral #nutrition with conventional or fish oil containing #lipid #emulsions
📌Contrary to our hypothesis, the use of FO containing IV lipid emulsions for the routine PN of the preterm infant did not improve lung growth compared to the infants who received conventional IV lipid emulsions.
🔗https://doi.org/10.1002/ppul.24938
👉Oxygen saturation to fraction of inspired oxygen ratio in preterm infants on routine #parenteral #nutrition with conventional or fish oil containing #lipid #emulsions
📌Contrary to our hypothesis, the use of FO containing IV lipid emulsions for the routine PN of the preterm infant did not improve lung growth compared to the infants who received conventional IV lipid emulsions.
🔗https://doi.org/10.1002/ppul.24938
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👉A Randomized Trial of #Parenteral #Nutrition Using a Mixed Lipid Emulsion Containing #Fish Oil in Infants of Extremely Low Birth Weight: Neurodevelopmental Outcome at 12 and 24 Months Corrected Age, A Secondary Outcome Analysis
📌Parenteral nutrition using a mixed lipid #emulsion containing fish oil did not improve neurodevelopment of extremely low birth weight infants at 12 and 24 months corrected age.
🔗https://doi.org/10.1016/j.jpeds.2020.06.056
👉A Randomized Trial of #Parenteral #Nutrition Using a Mixed Lipid Emulsion Containing #Fish Oil in Infants of Extremely Low Birth Weight: Neurodevelopmental Outcome at 12 and 24 Months Corrected Age, A Secondary Outcome Analysis
📌Parenteral nutrition using a mixed lipid #emulsion containing fish oil did not improve neurodevelopment of extremely low birth weight infants at 12 and 24 months corrected age.
🔗https://doi.org/10.1016/j.jpeds.2020.06.056