👉Breast Milk–Acquired Cytomegalovirus in Premature Infants
📌Infection with human cytomegalovirus (CMV) is ubiquitous, with a global seroprevalence of approximately 85%. In all human history, most CMV infections have probably been acquired from breastfeeding. Hayes et al in 1972 demonstrated that CMV could be cultured in breast milk, and breastfeeding was proposed as a mechanism by which the virus could be transmitted to the neonate. Subsequent work showed that such postnatal infections are generally innocuous in full-term infants, in contrast to the potentially devastating neurodevelopmental and audiological consequences of CMV infections acquired in utero.
🔗https://jamanetwork.com/journals/jamapediatrics/article-abstract/2755410
#cmv #virus #cytomegalovirus #breastmilk #breastfeeding #neonatology #preterm #jama
📌Infection with human cytomegalovirus (CMV) is ubiquitous, with a global seroprevalence of approximately 85%. In all human history, most CMV infections have probably been acquired from breastfeeding. Hayes et al in 1972 demonstrated that CMV could be cultured in breast milk, and breastfeeding was proposed as a mechanism by which the virus could be transmitted to the neonate. Subsequent work showed that such postnatal infections are generally innocuous in full-term infants, in contrast to the potentially devastating neurodevelopmental and audiological consequences of CMV infections acquired in utero.
🔗https://jamanetwork.com/journals/jamapediatrics/article-abstract/2755410
#cmv #virus #cytomegalovirus #breastmilk #breastfeeding #neonatology #preterm #jama
👉Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies
📌In this study, EOS incidence and associated mortality disproportionately occurred in preterm infants. Contemporary cases have demonstrated the limitations of current GBS prevention strategies. The increase in E coli infections among very low-birth-weight infants warrants continued study. Ampicillin and gentamicin remained effective antibiotics in most cases, but ongoing surveillance should monitor antibiotic susceptibilities of EOS pathogens.
🔗https://jamanetwork.com/journals/jamapediatrics/article-abstract/2765163
#sepsis #streptococcus #ecoli #jama #eos #neonatology #infection
📌In this study, EOS incidence and associated mortality disproportionately occurred in preterm infants. Contemporary cases have demonstrated the limitations of current GBS prevention strategies. The increase in E coli infections among very low-birth-weight infants warrants continued study. Ampicillin and gentamicin remained effective antibiotics in most cases, but ongoing surveillance should monitor antibiotic susceptibilities of EOS pathogens.
🔗https://jamanetwork.com/journals/jamapediatrics/article-abstract/2765163
#sepsis #streptococcus #ecoli #jama #eos #neonatology #infection
👉Testing Individuals for Coronavirus Disease 2019 (COVID-19)
📌PCR Test
🔗https://jamanetwork.com/journals/jama/fullarticle/2764238
#pcr #infographics #infections #jama #virus #testing
📌PCR Test
🔗https://jamanetwork.com/journals/jama/fullarticle/2764238
#pcr #infographics #infections #jama #virus #testing
👉Guidelines for Management of Neonatal Hypoglycemia
Are They Actually Applicable?
🔗https://jamanetwork.com/journals/jamapediatrics/fullarticle/2765824
#glucose #hypoglycemia #jama #neonatology #guide
Are They Actually Applicable?
🔗https://jamanetwork.com/journals/jamapediatrics/fullarticle/2765824
#glucose #hypoglycemia #jama #neonatology #guide
👉Associations Between Maternal Antenatal Corticosteroid Treatment and Mental and Behavioral Disorders in Children
📌In this population-based cohort study, exposure to maternal antenatal corticosteroid treatment was significantly associated with mental and behavioral disorders in children. These findings may help inform decisions about maternal antenatal corticosteroid treatment.
🔗https://jamanetwork.com/journals/jama/article-abstract/2766162
Commentary: https://jamanetwork.com/journals/jama/article-abstract/2766139
#rds #corticosteroid #jama
📌In this population-based cohort study, exposure to maternal antenatal corticosteroid treatment was significantly associated with mental and behavioral disorders in children. These findings may help inform decisions about maternal antenatal corticosteroid treatment.
🔗https://jamanetwork.com/journals/jama/article-abstract/2766162
Commentary: https://jamanetwork.com/journals/jama/article-abstract/2766139
#rds #corticosteroid #jama
👉Revisiting Leonardo da Vinci’s Vitruvian Man Using Contemporary Measurements
📌Five hundred years ago, Leonardo da Vinci attempted to memorialize Vitruvius’ description of man’s ideal human body. To do this, he manually measured proportions and combined them,1,2 creating one of the most famous drawings of the human body in the world—Vitruvian Man.3-5 Today, precise anthropometric body lengths can be obtained rapidly on large numbers of individuals. We repeated his approach using contemporary body scanning measurements to determine what Vitruvius’ proportions would be in this modern data set and how they would appear if drawn in the style of Vitruvian Man. We also extended the process to women.
🔗https://jamanetwork.com/journals/jama/fullarticle/2766854
#jama #davinci
📌Five hundred years ago, Leonardo da Vinci attempted to memorialize Vitruvius’ description of man’s ideal human body. To do this, he manually measured proportions and combined them,1,2 creating one of the most famous drawings of the human body in the world—Vitruvian Man.3-5 Today, precise anthropometric body lengths can be obtained rapidly on large numbers of individuals. We repeated his approach using contemporary body scanning measurements to determine what Vitruvius’ proportions would be in this modern data set and how they would appear if drawn in the style of Vitruvian Man. We also extended the process to women.
🔗https://jamanetwork.com/journals/jama/fullarticle/2766854
#jama #davinci
👉Association Between Proton Pump Inhibitor Use and Risk of Fracture in Children
📌These data suggest that PPI use is associated with a small increased risk of fracture in children; the findings inform safety considerations when these drugs are prescribed to pediatric patients.
🔗https://jamanetwork.com/journals/jamapediatrics/fullarticle/2762641
#jama #ppi #fractures
📌These data suggest that PPI use is associated with a small increased risk of fracture in children; the findings inform safety considerations when these drugs are prescribed to pediatric patients.
🔗https://jamanetwork.com/journals/jamapediatrics/fullarticle/2762641
#jama #ppi #fractures
👉Determination of Brain Death/Death by Neurologic CriteriaThe World Brain Death Project
📌This report provides recommendations for the minimum clinical standards for determination of#brain #death/death by #neurologic criteria in adults and children with clear guidance for various clinical circumstances. The recommendations have widespread international society endorsement and can serve to guide professional societies and countries in the revision or development of protocols and procedures for determination of brain death/death by neurologic criteria, leading to greater consistency within and between countries. #jama
🔗https://jamanetwork.com/journals/jama/fullarticle/2769149
📌This report provides recommendations for the minimum clinical standards for determination of#brain #death/death by #neurologic criteria in adults and children with clear guidance for various clinical circumstances. The recommendations have widespread international society endorsement and can serve to guide professional societies and countries in the revision or development of protocols and procedures for determination of brain death/death by neurologic criteria, leading to greater consistency within and between countries. #jama
🔗https://jamanetwork.com/journals/jama/fullarticle/2769149