Pediatrics & Neonatology
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New knowledge for pediatricians and neonatologists.
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👉Biomarkers and Disease Severity in Children With Community-Acquired Pneumonia

📌WBC count, ANC, CRP, and procalcitonin are generally not useful to discriminate nonsevere from severe disease in children with CAP, although CRP and procalcitonin may have some utility in predicting the most severe outcomes.

🔗https://pediatrics.aappublications.org/content/145/6/e20193728

#pneumonia #crp #pct #respiration #aap #pulmonology #infections #pediatrics
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👉C-Reactive Protein, Procalcitonin, and White Blood Count to Rule Out Neonatal Early-onset #Sepsis Within 36 Hours: A Secondary Analysis of the Neonatal #Procalcitonin Intervention Study

📌Normal serial #CRP and #PCT measurements within 36 hours after the start of empiric antibiotic therapy can exclude the presence of neonatal #EOS with a high probability. The negative predictive values of CRP and PCT do not increase after 36 hours.

🔗https://doi.org/10.1093/cid/ciaa876