Pediatrics & Neonatology
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๐Ÿ‘‰Typical RSV cough: myth or reality? A diagnostic accuracy study

๐Ÿ“ŒRespiratory syncytial virus (RSV) is well known for causing a potentially severe course of bronchiolitis in infants. Many paediatric healthcare workers claim to be able to diagnose RSV based on cough sound, which was evaluated in this study. Parents of children < 1 year old admitted to the paediatric ward because of airway complaints were asked to record cough sounds of their child. In all children, MLPA analysisโ€”a variation of PCR analysisโ€”on nasopharyngeal swab was performed (golden standard). Sixteen cough fragments representing 4 different viral pathogens were selected and presented to paediatric healthcare workers. Thirty-two paediatric nurses, 16 residents and 16 senior staff members were asked to classify the audio files and state whether the cough was due to RSV infection or not. Senior staff, nurses and residents correctly identified RSV with a sensitivity of 76.2%, 73.1% and 51.3% respectively. Correct exclusion of RSV cases was performed with a specificity of 60.8%, 60.2% and 65.3% respectively. Sensitivity ranged from 0 to 100% between colleagues; no one correctly identified all negatives. Residents had significantly lower rates of sensitivity than senior staff and nurses. This was strongly related to work experience, in which more than 3.5 years of work experience was related to the best result.

๐Ÿ”—https://link.springer.com/article/10.1007%2Fs00431-020-03709-1

#cough #rsv #infections #pulmonology #springer
๐Ÿ‘‰When the Cough Does Not Improve: A Review on Protracted Bacterial Bronchitis in Children

๐Ÿ“ŒChronic #cough is defined as a daily cough that persists longer than 4 weeks. Protracted bacterial #bronchitis (PBB) is a common cause of chronic wet cough in preschool children with no symptoms or signs of other specific causes, and resolution usually follows a 2-week course of an appropriate oral antibiotic. The diagnosis is mainly clinical; generally, no instrumental examinations are necessary...

๐Ÿ”—https://doi.org/10.3389/fped.2020.00433