#Paracetamol (Acetaminophen) and the Developing Brain

https://doi.org/10.3390/ijms222011156

Within each #food category, products with sugars as an added ingredient had a less desirable nutrient profile compared to those that did not have sugar-contributing ingredients

#babyfood
https://doi.org/10.3390/nu13093105

A positive association was seen between #iron dose at 60 days and cognitive outcomes. Our results suggest that increased iron supplementation in infants born preterm, at the doses administered in the PENUT Trial, may have positive neurodevelopmental effects, particularly in infants treated with Epo

https://doi.org/10.1016/j.jpeds.2021.07.019

The trial intends to ascertain whether there are potential advantages to the BLISS #complementary feeding method in this specific population, generating data to support families and healthcare providers

#babyfood
https://doi.org/10.1186/s13063-021-05647-1

The #extubation procedure is associated with significant changes in FRC. This study provides novel information for determining the optimal way of extubating a preterm infant

https://doi.org/10.1038/s41390-021-01699-w

The purpose of this review is to place into context the #platelet and its role in immunology and examine the evidence where available for its role as an immune cell in childhood #sepsis.

https://doi.org/10.1038/s41390-021-01715-z

Anti-#reflux medications are frequently prescribed in very preterm infants, despite evidence to suggest that they are not effective and may be harmful.

https://doi.org/10.1038/s41390-021-01821-y

#Extubation failure within 72 h in infants less than 37 weeks of gestation did not differ between the two groups.

https://doi.org/10.1007/s00431-021-04084-1

Medication Use in the Neonatal Intensive Care Unit and Changes from 2010 to 2018

https://youtu.be/4D6jm8cysAU

An important strategy to improve survival free of major neuro-developmental disability is to birth extremely preterm infants in a tertiary perinatal center, where specialist obstetric care for the mother and ongoing intensive care for the infant can both be provided without the potential morbidities associated with postnatal transfer.

#development
https://doi.org/10.1016/j.semperi.2021.151479

Among 5.5-year-old very preterm born children, subgroups can be distinguished with distinct outcome profiles that vary in severity, type, and combinations of deficits.

#development

Recommendations for neuro #imaging in neonates with NE are presented.

https://doi.org/10.1016/j.siny.2021.101304

#LUS is a promising method to diagnose TTN. Only DLP is not enough to diagnose #TTN, while DLP combined with B-line has good diagnostic performance.

https://doi.org/10.1016/j.jped.2021.10.003

Treatment of neonatal #seizures may be time-critical, but more research is needed to confirm this. Improvements in neonatal seizure diagnosis and treatment are also needed.

https://doi.org/10.1016/j.jpeds.2021.09.058

Findings demonstrate an association between impaired motor function and brain organisation in school-age children treated with therapeutic hypothermia for neonatal hypoxic-ischaemic #encephalopathy.

https://doi.org/10.1016/j.nicl.2021.102872

 Febrile urinary tract infection (UTI) is the most frequent cause of serious bacterial illness in children aged <2 years.
 Empiric antibiotic treatment must be initiated soon after a urine specimen for culture has been obtained.
 The increase in antibiotic resistance of uropathogens requires continuous monitoring.
 To limit the emergence of resistance, every effort to reduce and rationalize antibiotic consumption must be made.
 An increased use of antibiotic stewardship can be greatly effective for antibiotic
resistance.

https://doi.org/10.1016/j.jgar.2021.11.003

After the Baby-Friendly Hospital Initiative and Baby-Friendly Hospital Initiative for neonatal wards (Neo-BFHI) interventions were concluded, we found significant improvements in the breastfeeding attitudes of healthcare professionals
and in #breastfeeding-related care practices.

https://doi.org/10.1177/08903344211058373

This review summarizes the current state of the art in AE research/

#allergy
DOI: 10.1111/all.15058

The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin. Clinicians may consider the addition of broader-spectrum therapy among newborns at highest risk of EOS, but we caution that neither the substitution nor the addition of 1 single antimicrobial agent is likely to provide adequate empiric therapy in all cases.

Births at GA 41 +4–­42+0 weeks were associated with an increased risk of neonatal morbidity and birth complications compared with births at GA 41+0–­41+3 weeks. The results of this study may aid clinicians in deciding when to recommend induction of labor in late-­term pregnancies.

DOI: 10.1111/aogs.14299