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👉Challenges in developing a consensus definition of neonatal sepsis
📌Sepsis remains a leading cause of morbidity and mortality in the neonatal population, and at present, there is no unified definition of neonatal sepsis. Existing consensus sepsis definitions within paediatrics are not suited for use in the NICU and do not address sepsis in the premature population. Many neonatal research and surveillance networks have criteria for the definition of sepsis within their publications though these vary greatly and there is typically a heavy emphasis on microbiological culture. The concept of organ dysfunction as a diagnostic criterion for sepsis is rarely considered in neonatal literature, and it remains unclear how to most accurately screen neonates for organ dysfunction. Accurately defining and screening for sepsis is important for clinical management, health service design and future research. The progress made by the Sepsis-3 group provides a roadmap of how definitions and screening criteria may be developed. Similar initiatives in neonatology are likely to be more challenging and would need to account for the unique presentation of sepsis in term and premature neonates. The outputs of similar consensus work within neonatology should be twofold: a validated definition of neonatal sepsis and screening criteria to identify at-risk patients earlier in their clinical course.
🔗https://www.nature.com/articles/s41390-020-0785-x
#sepsis #nature #nicu
👉Challenges in developing a consensus definition of neonatal sepsis
📌Sepsis remains a leading cause of morbidity and mortality in the neonatal population, and at present, there is no unified definition of neonatal sepsis. Existing consensus sepsis definitions within paediatrics are not suited for use in the NICU and do not address sepsis in the premature population. Many neonatal research and surveillance networks have criteria for the definition of sepsis within their publications though these vary greatly and there is typically a heavy emphasis on microbiological culture. The concept of organ dysfunction as a diagnostic criterion for sepsis is rarely considered in neonatal literature, and it remains unclear how to most accurately screen neonates for organ dysfunction. Accurately defining and screening for sepsis is important for clinical management, health service design and future research. The progress made by the Sepsis-3 group provides a roadmap of how definitions and screening criteria may be developed. Similar initiatives in neonatology are likely to be more challenging and would need to account for the unique presentation of sepsis in term and premature neonates. The outputs of similar consensus work within neonatology should be twofold: a validated definition of neonatal sepsis and screening criteria to identify at-risk patients earlier in their clinical course.
🔗https://www.nature.com/articles/s41390-020-0785-x
#sepsis #nature #nicu
👉Nasal mask vs binasal prongs for nasal continuous positive airway pressure in preterm infants: A systematic review and meta‐analysis
📌Among premature infants, NCPAP provided with NM is more effective in preventing intubation and mechanical ventilation within 72 hours of initiating the support compared with NCPAP provided with BNP.
🔗https://onlinelibrary.wiley.com/doi/abs/10.1002/ppul.24878
#cpap #respiration #preterm #nicu #wiley
📌Among premature infants, NCPAP provided with NM is more effective in preventing intubation and mechanical ventilation within 72 hours of initiating the support compared with NCPAP provided with BNP.
🔗https://onlinelibrary.wiley.com/doi/abs/10.1002/ppul.24878
#cpap #respiration #preterm #nicu #wiley
👉Hospitalising preterm infants in single family rooms versus open bay units: A systematic review and meta-analysis of impact on parents
📌Single family rooms seem to facilitate parental presence, involvement, skin-to-skin care, and reduce NICU-related parental stress.
🔗https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30132-2/fulltext
#nicu #lancet #skintoskin #hospitalising
📌Single family rooms seem to facilitate parental presence, involvement, skin-to-skin care, and reduce NICU-related parental stress.
🔗https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30132-2/fulltext
#nicu #lancet #skintoskin #hospitalising
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👉Elective Replacement of Peripheral Intravenous Cannulas in Neonates
📌Elective replacement of peripheral intravenous cannulas was not shown to reduce the risk of combined adverse events. Elective peripheral intravenous cannula replacement also incurred a higher cost.
🔗https://pubmed.ncbi.nlm.nih.gov/32524888/
#nicu #cannula #infusion
👉Elective Replacement of Peripheral Intravenous Cannulas in Neonates
📌Elective replacement of peripheral intravenous cannulas was not shown to reduce the risk of combined adverse events. Elective peripheral intravenous cannula replacement also incurred a higher cost.
🔗https://pubmed.ncbi.nlm.nih.gov/32524888/
#nicu #cannula #infusion
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👉Family Rooms in Neonatal Intensive Care Units and Neonatal Outcomes: An International Survey and Linked Cohort Study
📌Neonates from units with infant-parent #rooms had lower odds of mortality or major morbidity (aOR, 0.76; 95% CI, 0.64-0.89), including lower odds of sepsis and bronchopulmonary dysplasia, than those from units without infant-parent rooms. #NICU #afif
🔗https://www.sciencedirect.com/science/article/abs/pii/S0022347620307101?dgcid=coauthor
👉Family Rooms in Neonatal Intensive Care Units and Neonatal Outcomes: An International Survey and Linked Cohort Study
📌Neonates from units with infant-parent #rooms had lower odds of mortality or major morbidity (aOR, 0.76; 95% CI, 0.64-0.89), including lower odds of sepsis and bronchopulmonary dysplasia, than those from units without infant-parent rooms. #NICU #afif
🔗https://www.sciencedirect.com/science/article/abs/pii/S0022347620307101?dgcid=coauthor
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👉#Family Integrated Care for Preterm Infants in China: A Cluster Randomized Controlled Trial
📌#FICare was feasible in Chinese neonatal intensive care units and was associated with reduced hospital LOS, medical expenditures, and rates of adverse outcomes. #NICU
🔗https://doi.org/10.1016/j.jpeds.2020.09.006
👉#Family Integrated Care for Preterm Infants in China: A Cluster Randomized Controlled Trial
📌#FICare was feasible in Chinese neonatal intensive care units and was associated with reduced hospital LOS, medical expenditures, and rates of adverse outcomes. #NICU
🔗https://doi.org/10.1016/j.jpeds.2020.09.006
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👉#Resuscitation of non-vigorous neonates born through #meconium-stained amniotic fluid: post policy change impact analysis
📌The policy change towards not routinely suctioning non-vigorous neonates born through MSAF at birth was not associated with an increase in the local incidence of #MAS and was associated with fewer #NICU admissions.
🔗https://doi.org/10.1136/archdischild-2020-319771
https://pediatrics.aappublications.org/content/142/6/e20181485/tab-figures-data
👉#Resuscitation of non-vigorous neonates born through #meconium-stained amniotic fluid: post policy change impact analysis
📌The policy change towards not routinely suctioning non-vigorous neonates born through MSAF at birth was not associated with an increase in the local incidence of #MAS and was associated with fewer #NICU admissions.
🔗https://doi.org/10.1136/archdischild-2020-319771
https://pediatrics.aappublications.org/content/142/6/e20181485/tab-figures-data