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تنها مرجع تخصصی ارائه خدمات پژوهشی در علوم‌پزشکی

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مقاله شماره ۳۸
#Oncology
#BreastCancer
#Epidemiology

عنوان:
Risk factors for breast cancer among young women in southern iran

مجله:
IJC ( International Journal of Cancer)

نوع مطالعه:
Case_control study

تاریخ انتشار:
Nov, 09, 2010

سایتیشن:
Ghiasvand et al.

چکیده:
Age standardized incidence rates of breast cancer in developed countries is nearly threefold higher than in developing countries. Iran has had one of the lowest incidence rates for breast cancer in the world, but during the last four decades increasing incidence rates of breast cancer made it the most prevalent cancer in Iranian women. After adjustment for age, Iranian young women are at relatively higher risk of breast cancer than their counterparts in developed countries. The purpose of this study was to investigate some established risk factors of breast cancer in Iranian young women. A hospital‐based case control study comprising 521 women with histologically confirmed, incident breast cancer and 521 controls frequency‐matched by age and province of residence was conducted. Logistic regression performed to investigate associations of reproductive and anthropometric factors with breast cancer risk. In multivariate analysis, family history [odds ratio (OR): 1.61; 95% confidence interval (CI): 1.07–2.42], oral contraceptives (OC) usage (OR: 1.52; 95% CI: 1.11–2.08), low parity (OR parity ≥ 3 vs. 1–2: 0.33; 95% CI: 0.23–0.49), employment (OR: 1.83; 95% CI: 1.05–3.23) and shorter period of breast feeding (OR ≥ 37 months vs. < 37: 0.61; 95% CI: 0.44–0.84) were related to a higher risk of breast cancer in young women. This was the first study focusing on risk factors of breast cancer in Iranian young women. The trend of decreasing parity and shortened duration of breast feeding along with OC usage might partly explain the rapid rising of breast cancer incidence in Iranian young women.

توضیحات مهم:
نویسندگان در این مطالعه به بررسی ریسک فاکتورهای سرطان سینه در زنان جوان جنوب ایران پرداخته اند.
در این مطالعه مورد_شاهدی ۵۲۱ مورد تایید شده سرطان سینه توسط پاتولوژی و ۵۲۱ شاهد بررسی شدند.
نتایج حاکی از آن بود که سابقه ی فامیلی ، مصرف ocp ، نا برابری اجتماعی و کوتاه بودن زمان شیردهی با ریسک بالاتری از سرطان سینه همراه بودند.
در این مطالعه علت افزایش سرطان سینه در زنان جوان ایرانی در دهه های اخیر را مصرف ocp ، طول شیردهی کم و نابرابری در نظر گرفت.
Pdf 👉🏻 https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.25748

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