#Т3_чистый_дозировки
Dosing with T3-only (or with low-dose NDT, or the combination of T4/T3, or T3 by itself)
A healthy thyroid produces five hormones: T4, T3, T2, T1 and calcitonin. T4 is a storage hormone meant to covert to the active T3 thyroid hormone. But a healthy thyroid also gives some direct T3 i.e. it doesn’t force you to live for conversion alone! T3 is the thyroid hormone which gives massive benefits as far as our health, immune function, energy and overall well-being! You can read more about T3 in that very chapter within the revised STTM book.
What are prescription brands of T3 (Liothyronine Sodium)?
Cytomel is well-known in the US and Canada, as is Cynomel in Mexico. But there are also now many other good generics or brands. Other worldwide brands include Tertroxin, Linomel, Cyronine, Unipharma, Ti-Tre, Tironina, Tiromel, Trijodthyronin and more. All brands of T3 are synthetic, but work well according to patient reports as long as one has optimal cortisol levels. You can see most brands and fillers at the bottom part of this page.
If patients add synthetic T3 (liothyronine) to their synthetic T4 (thyroxine), how does it work? What is optimal?
A lot of patients have reported that it works best for them to dose the T3 three times a day because of its short half-life, such as first thing in the morning, about 4 hours later, and another 4 hours after that. Some might add a small amount like 2.5 mcg at bedtime, but that’s individual–it helps some sleep better; others it keeps awake.
We have noted that it doesn’t matter when the T4 is taken (it will be converting to T3 all the time in the background). For convenience sake, the T4 can still be taken once a day in the morning, or at bedtime.
When on the T4/T3 combination, patients have noted that optimal equals a free T3 towards the top area of the range, and a free T4 right around mid-range. Why only around mid-range for free T4 or very slightly above? Because over time, patients started to see an increase in RT3, the inactive hormone, if they went too far above mid-range.
Do some hypothyroid patients use nothing but T3-only (liothyronine)?
Yes, some might choose to be use nothing but T3. But you can’t forget a dose, as you’ll not have any T4 converting to T3 in the background for you.
Some might be using mostly T3 to help lower high Reverse T3, the inactive hormone. RT3 can go up due to low iron, high cortisol, chronic inflammation, after surgery, any injury, Lyme, mold illness..to name a few.
If patients move from natural desiccated thyroid or T4/T3 to just T3, how does it work?
Some patients have stopped NDT or the synthetic T4/T3 combo one day, and started on T3-only the next. But it has to be in very small amounts until the T4, and its conversion to T3, falls, before raising too much.
When optimal on nothing more than T3-only, patients report they achieve a free T3 at the very top if not slightly over. Free T4 will naturally be quite low and patients have not found that to be a problem as long as they are multi-dosing the T3.
If patients use T3 in any way, how does it work?
Generally, if one is not used to being on T3, reported starting doses are 5 mcg in the morning, and another 5 mcg when one’s signs (BP, heartrate, etc) and symptoms (tiredness) dictate it, etc–that’s usually about 4 hours after the first dose. A third 5 mcg dose is added about four hours later. If someone might have reason to be particularly sensitive to the strength of T3, they could do 2.5 mcg each dose, we have learned.
Raising in small amounts every week seems to work, too, in the quest to achieve an optimal free T3 lab result.
How do patients avoid problems when using T3?
One hard-earned lesson is that having a cortisol problem will cause problems/bad reactions with raising. That’s why patients report that it’s imperative to check one’s cortisol levels via saliva testing. The adrenal info page has Discovery Steps, or you can go here to order your own saliva cortisol test.
Dosing with T3-only (or with low-dose NDT, or the combination of T4/T3, or T3 by itself)
A healthy thyroid produces five hormones: T4, T3, T2, T1 and calcitonin. T4 is a storage hormone meant to covert to the active T3 thyroid hormone. But a healthy thyroid also gives some direct T3 i.e. it doesn’t force you to live for conversion alone! T3 is the thyroid hormone which gives massive benefits as far as our health, immune function, energy and overall well-being! You can read more about T3 in that very chapter within the revised STTM book.
What are prescription brands of T3 (Liothyronine Sodium)?
Cytomel is well-known in the US and Canada, as is Cynomel in Mexico. But there are also now many other good generics or brands. Other worldwide brands include Tertroxin, Linomel, Cyronine, Unipharma, Ti-Tre, Tironina, Tiromel, Trijodthyronin and more. All brands of T3 are synthetic, but work well according to patient reports as long as one has optimal cortisol levels. You can see most brands and fillers at the bottom part of this page.
If patients add synthetic T3 (liothyronine) to their synthetic T4 (thyroxine), how does it work? What is optimal?
A lot of patients have reported that it works best for them to dose the T3 three times a day because of its short half-life, such as first thing in the morning, about 4 hours later, and another 4 hours after that. Some might add a small amount like 2.5 mcg at bedtime, but that’s individual–it helps some sleep better; others it keeps awake.
We have noted that it doesn’t matter when the T4 is taken (it will be converting to T3 all the time in the background). For convenience sake, the T4 can still be taken once a day in the morning, or at bedtime.
When on the T4/T3 combination, patients have noted that optimal equals a free T3 towards the top area of the range, and a free T4 right around mid-range. Why only around mid-range for free T4 or very slightly above? Because over time, patients started to see an increase in RT3, the inactive hormone, if they went too far above mid-range.
Do some hypothyroid patients use nothing but T3-only (liothyronine)?
Yes, some might choose to be use nothing but T3. But you can’t forget a dose, as you’ll not have any T4 converting to T3 in the background for you.
Some might be using mostly T3 to help lower high Reverse T3, the inactive hormone. RT3 can go up due to low iron, high cortisol, chronic inflammation, after surgery, any injury, Lyme, mold illness..to name a few.
If patients move from natural desiccated thyroid or T4/T3 to just T3, how does it work?
Some patients have stopped NDT or the synthetic T4/T3 combo one day, and started on T3-only the next. But it has to be in very small amounts until the T4, and its conversion to T3, falls, before raising too much.
When optimal on nothing more than T3-only, patients report they achieve a free T3 at the very top if not slightly over. Free T4 will naturally be quite low and patients have not found that to be a problem as long as they are multi-dosing the T3.
If patients use T3 in any way, how does it work?
Generally, if one is not used to being on T3, reported starting doses are 5 mcg in the morning, and another 5 mcg when one’s signs (BP, heartrate, etc) and symptoms (tiredness) dictate it, etc–that’s usually about 4 hours after the first dose. A third 5 mcg dose is added about four hours later. If someone might have reason to be particularly sensitive to the strength of T3, they could do 2.5 mcg each dose, we have learned.
Raising in small amounts every week seems to work, too, in the quest to achieve an optimal free T3 lab result.
How do patients avoid problems when using T3?
One hard-earned lesson is that having a cortisol problem will cause problems/bad reactions with raising. That’s why patients report that it’s imperative to check one’s cortisol levels via saliva testing. The adrenal info page has Discovery Steps, or you can go here to order your own saliva cortisol test.
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