и тебя отсеквенируем
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Журнальный клуб по современной биологии.

https://tttttt.me/compbio?boost

Про single cell, геномику, биоинформатику и не только.
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Некоторые геномы из 2016.

- De novo assembly and phasing of a Korean human genome http://www.nature.com/nature/journal/v538/n7624/pdf/nature20098.pdf
- Evolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper http://www.nature.com/articles/ncomms13107.pdf
- The population genomics of rhesus macaques (Macaca mulatta)
based on whole genome sequences http://genome.cshlp.org/content/early/2016/10/17/gr.204255.116.full.pdf
- Comparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly http://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1071-4
- The seahorse genome and the evolution of its specialized morphology http://www.nature.com/nature/journal/v540/n7633/full/nature20595.html

#genomes
А вот снова про хроматин.

- The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries http://www.cell.com/molecular-cell/fulltext/S1097-2765(17)30164-8
- Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition http://www.nature.com/nature/journal/v544/n7648/full/nature21711.html
- 3D structures of individual mammalian genomes studied by single-cell Hi-C http://www.nature.com/nature/journal/v544/n7648/full/nature21429.html
- Complex multi-enhancer contacts captured by genome architecture mapping http://www.nature.com/nature/journal/v543/n7646/full/nature21411.html

#chromatin #epigenetics #genomes