Подборка про хроматин и эпигенетику.
- Лонгрид в The New Yorker: http://www.newyorker.com/magazine/2016/05/02/breakthroughs-in-epigenetics
- Иллюстрация достижений в эпигенетике от Scientific American: https://blogs.scientificamerican.com/sa-visual/gene-regulation-illustrated/
- Specification and epigenetic programming of the human germ line http://www.nature.com/nrg/journal/v17/n10/full/nrg.2016.88.html
- The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-016-0089-x
- Targeted degradation of CTCF decouples local insulation of chromosome domains from higher‐order genomic compartmentalization http://biorxiv.org/content/biorxiv/early/2016/12/21/095802.full.pdf
#chromatin #epigenetics
- Лонгрид в The New Yorker: http://www.newyorker.com/magazine/2016/05/02/breakthroughs-in-epigenetics
- Иллюстрация достижений в эпигенетике от Scientific American: https://blogs.scientificamerican.com/sa-visual/gene-regulation-illustrated/
- Specification and epigenetic programming of the human germ line http://www.nature.com/nrg/journal/v17/n10/full/nrg.2016.88.html
- The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-016-0089-x
- Targeted degradation of CTCF decouples local insulation of chromosome domains from higher‐order genomic compartmentalization http://biorxiv.org/content/biorxiv/early/2016/12/21/095802.full.pdf
#chromatin #epigenetics
The New Yorker
Same but Different
How the field of epigenetics complicates the nature-versus-nurture debate.
А вот снова про хроматин.
- The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries http://www.cell.com/molecular-cell/fulltext/S1097-2765(17)30164-8
- Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition http://www.nature.com/nature/journal/v544/n7648/full/nature21711.html
- 3D structures of individual mammalian genomes studied by single-cell Hi-C http://www.nature.com/nature/journal/v544/n7648/full/nature21429.html
- Complex multi-enhancer contacts captured by genome architecture mapping http://www.nature.com/nature/journal/v543/n7646/full/nature21411.html
#chromatin #epigenetics #genomes
- The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries http://www.cell.com/molecular-cell/fulltext/S1097-2765(17)30164-8
- Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition http://www.nature.com/nature/journal/v544/n7648/full/nature21711.html
- 3D structures of individual mammalian genomes studied by single-cell Hi-C http://www.nature.com/nature/journal/v544/n7648/full/nature21429.html
- Complex multi-enhancer contacts captured by genome architecture mapping http://www.nature.com/nature/journal/v543/n7646/full/nature21411.html
#chromatin #epigenetics #genomes