✨Fair splits flip the leaderboard: CHANRG reveals limited generalization in RNA secondary-structure prediction

📝 Summary:
The CHANRG benchmark reveals RNA foundation models achieve high held-out accuracy but lose significant robustness out-of-distribution. This new benchmark provides a stricter framework for evaluating RNA secondary structure prediction.

🔹 Publication Date: Published on Mar 20

🔹 Paper Links:
• arXiv Page: https://arxiv.org/abs/2603.22330
• PDF: https://arxiv.org/pdf/2603.22330
• Project Page: https://huggingface.co/datasets/multimolecule/chanrg
• Github: https://github.com/MultiMolecule/multimolecule

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#RNAstructure #MachineLearning #FoundationModels #Bioinformatics #ModelRobustness