The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold
https://www.isomorphiclabs.com/articles/the-isomorphic-labs-drug-design-engine-unlocks-a-new-frontier
https://www.isomorphiclabs.com/articles/the-isomorphic-labs-drug-design-engine-unlocks-a-new-frontier
Isomorphiclabs
The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing us to rationally design new medicines on a computer with…
DrDroid (YC W23) Is Hiring
https://www.ycombinator.com/companies/drdroid/jobs/w45QcNV-product-engineer-assignment-mandatory
https://www.ycombinator.com/companies/drdroid/jobs/w45QcNV-product-engineer-assignment-mandatory
Y Combinator
Product Engineer [Assignment mandatory] at DrDroid | Y Combinator
We’re expanding our team and hiring a product engineer:
- Experience of understanding user / product requirements and building it right.
- Understands distributed systems and why production is different from a code repository.
- Has all the energy…
- Experience of understanding user / product requirements and building it right.
- Understands distributed systems and why production is different from a code repository.
- Has all the energy…
Moonstone: Modern, cross-platform Lua runtime and package manager written in Zig
https://moonstone.sh/
https://moonstone.sh/
Mac gaming is finally getting the overpowered upgrade it deserves
https://www.macworld.com/article/3189951/apples-latest-game-porting-toolkit-beta-changed-how-i-think-about-mac-gaming.html
https://www.macworld.com/article/3189951/apples-latest-game-porting-toolkit-beta-changed-how-i-think-about-mac-gaming.html
Macworld
Mac gaming is finally getting the overpowered upgrade it deserves
Game Porting Toolkit 4 beta is the clearest sign that gaming is becoming a priority for Apple.
Show HN: Find someone in the dark – light them or light yourself? (Three.js)
https://github.com/skorotkiewicz/signal-in-the-dark
https://github.com/skorotkiewicz/signal-in-the-dark
GitHub
GitHub - skorotkiewicz/signal-in-the-dark: What is more effective? A 3D simulator of finding someone in the dark – shine the light…
What is more effective? A 3D simulator of finding someone in the dark – shine the light on yourself or on them? - skorotkiewicz/signal-in-the-dark
The Computer at the Bottom of a Canal
https://negroniventurestudios.com/2026/07/18/the-computer-at-the-bottom-of-a-canal/
https://negroniventurestudios.com/2026/07/18/the-computer-at-the-bottom-of-a-canal/
Negroni Venture Studios
The computer at the bottom of a canal
Somewhere at the bottom of the Forth and Clyde Canal, buried in the silt, there is a box of custom silicon that was right about almost everything. Back in 1988 a Scottish hi-fi company shipped a processor that checked the type and bounds of every memory access…
LG monitors silently install software through Windows Update without consent
https://videocardz.com/newz/lg-monitors-silently-install-software-through-windows-update-without-user-consent
https://videocardz.com/newz/lg-monitors-silently-install-software-through-windows-update-without-user-consent
Why do AI company logos look like buttholes?
https://velvetshark.com/ai-company-logos-that-look-like-buttholes
https://velvetshark.com/ai-company-logos-that-look-like-buttholes
VelvetShark
Why do AI company logos look like buttholes?
A humorous exploration of the uncanny resemblance between AI company logos and human anatomy. Discover why circular, gradient-based designs dominate the AI industry, and what this design convergence tells us about branding in tech.
What AI did to stackoverflow in a graph
https://data.stackexchange.com/stackoverflow/query/1953768#graph
https://data.stackexchange.com/stackoverflow/query/1953768#graph
GPT-5.6 used a prompt to close a 30-year gap in convex optimization
https://old.reddit.com/r/math/comments/1uxj3cy/after_openais_cdc_proof_announcement_gpt56_used_a/
https://old.reddit.com/r/math/comments/1uxj3cy/after_openais_cdc_proof_announcement_gpt56_used_a/
Reddit
From the math community on Reddit: After OpenAI’s CDC proof announcement, GPT-5.6 used a similar prompt to close a 30-year gap…
Explore this post and more from the math community
Traders are increasingly betting against SpaceX just weeks after IPO
https://www.ft.com/content/2b96703d-440b-46db-8d86-9fff9ecc59d5
https://www.ft.com/content/2b96703d-440b-46db-8d86-9fff9ecc59d5
The Fermi Paradox, Percolation, and Inbreeding
https://reactormag.com/the-fermi-paradox-percolation-and-inbreeding/
https://reactormag.com/the-fermi-paradox-percolation-and-inbreeding/
Young adults are poor despite every metric which suggests otherwise
https://xcancel.com/i/article/2077113148524417439
https://xcancel.com/i/article/2077113148524417439
In Germany if you say a restaurant is just ok they send the gestapo after you
https://twitter.com/eigen_moomin/status/2077471686295957749
https://twitter.com/eigen_moomin/status/2077471686295957749
X (formerly Twitter)
eigen moomin (@eigen_moomin) on X
in germany if you say a restaurant is just ok they send the gestapo after you
What's the deal with all the random weekly quota resets for agents lately?
https://minimaxir.com/2026/07/agent-quota-reset/
https://minimaxir.com/2026/07/agent-quota-reset/
Max Woolf's Blog
What's the deal with all the random weekly quota resets for agents lately?
I’m going to be the weirdo who complains about literally getting free stuff.