Habitual coffee intake shapes the microbiome, modifies physiology and cognition
https://www.nature.com/articles/s41467-026-71264-8
https://www.nature.com/articles/s41467-026-71264-8
Nature
Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition
Nature Communications - Here, the authors investigate coffee’s impact on the microbiota–gut–brain axis and assess whether these effects occur independently of caffeine in healthy...
Familiarity is the enemy: On why Enterprise systems have failed for 60 years
https://felixbarbalet.com/familiarity-is-the-enemy/
https://felixbarbalet.com/familiarity-is-the-enemy/
Context is everything
Familiarity is the enemy
My thoughts on why enterprise knowledge systems have failed for sixty years, and what might finally replace them.
A couple of weeks ago I demoed one part of what I have been building to a senior exec at a global enterprise - someone who had been asked to…
A couple of weeks ago I demoed one part of what I have been building to a senior exec at a global enterprise - someone who had been asked to…
Show HN: How LLMs Work – Interactive visual guide based on Karpathy's lecture
https://ynarwal.github.io/how-llms-work/
https://ynarwal.github.io/how-llms-work/
S. Korea police arrest man over AI image of runaway wolf that misled authorities
https://www.bbc.com/news/articles/c4gx1n0dl9no
https://www.bbc.com/news/articles/c4gx1n0dl9no
Bbc
South Korea police arrest man for posting AI photo of runaway wolf
The widely circulated image had prompted authorities to move their search operation.
How to be anti-social – a guide to incoherent and isolating social experiences
https://nate.leaflet.pub/3mk4xkaxobc2p
https://nate.leaflet.pub/3mk4xkaxobc2p
n8
how to be anti-social - n8
a guide to incoherent and isolating social experiences
UK Biobank leak: Health details of 500 000 people are offered for sale
https://www.bmj.com/content/393/bmj.s781
https://www.bmj.com/content/393/bmj.s781
8087 Emulation on 8086 Systems
https://www.os2museum.com/wp/learn-something-old-every-day-part-xx-8087-emulation-on-8086-systems/
https://www.os2museum.com/wp/learn-something-old-every-day-part-xx-8087-emulation-on-8086-systems/
The operating cost of adult and gambling startups
https://orchidfiles.com/stigma-is-a-tax-on-every-operational-decision/
https://orchidfiles.com/stigma-is-a-tax-on-every-operational-decision/
Orchid Files
The hidden costs of gambling and adult businesses
In adult and gambling markets, even routine work gets harder: hiring, payments, ads, fundraising, and explaining what you do.
Sabotaging projects by overthinking, scope creep, and structural diffing
https://kevinlynagh.com/newsletter/2026_04_overthinking/
https://kevinlynagh.com/newsletter/2026_04_overthinking/
Norway Set to Become Latest Country to Ban Social Media for Under 16s
https://www.bloomberg.com/news/articles/2026-04-24/norway-wants-kids-to-be-kids-with-social-media-ban-for-under-16s
https://www.bloomberg.com/news/articles/2026-04-24/norway-wants-kids-to-be-kids-with-social-media-ban-for-under-16s
Bloomberg.com
Norway Set to Become Latest Country to Ban Social Media for Under 16s
Norway plans to restrict access to social media for children under 16, joining a growing number of countries responding to concerns about the potential harm kids face online.
Researchers Simulated a Delusional User to Test Chatbot Safety
https://www.404media.co/delusion-using-chatgpt-gemini-claude-grok-safety-ai-psychosis-study/
https://www.404media.co/delusion-using-chatgpt-gemini-claude-grok-safety-ai-psychosis-study/
404 Media
Researchers Simulated a Delusional User to Test Chatbot Safety
Grok and Gemini encouraged delusions and isolated users, while the newer ChatGPT model and Claude hit the emotional brakes.
Why I'm Done Making Desktop Applications (2009)
https://www.kalzumeus.com/2009/09/05/desktop-aps-versus-web-apps/
https://www.kalzumeus.com/2009/09/05/desktop-aps-versus-web-apps/